8 Medications You Should Never Take With Coffee

Antibiotics (Ciprofloxacin)

Coffee can interfere with ciprofloxacin absorption, reducing its effectiveness and potentially leading to antibiotic resistance or prolonged infections.

Thyroid Medications (Levothyroxine)

Coffee reduces the absorption of levothyroxine, making the medication less effective in managing thyroid hormone levels.

Sedatives (Diazepam)

Coffee's caffeine counters the calming effects of sedatives like diazepam, reducing their effectiveness and potentially worsening anxiety or insomnia.

Osteoporosis Medications (Alendronate)

Coffee reduces the absorption of alendronate, diminishing its effectiveness in strengthening bones and preventing fractures.

Bronchodilators (Theophylline)

Caffeine increases the side effects of theophylline, such as nausea and nervousness, by amplifying its stimulating effects.

Antipsychotics (Clozapine)

Coffee can interfere with clozapine metabolism, increasing the risk of toxic side effects like seizures and cardiac issues.

Stimulants (Adderall)

Coffee combined with Adderall can cause excessive stimulation, leading to increased heart rate, anxiety, and potential cardiovascular issues.

Iron Supplements

Coffee inhibits the absorption of iron from supplements, decreasing their effectiveness and potentially leading to iron deficiency anemia.

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